Activation of Cascade‐Like Antitumor Immune Responses through In Situ Doxorubicin Stimulation and Blockade of Checkpoint Coinhibitory Receptor TIGIT (Adv. Healthcare Mater. 1/2022)
نویسندگان
چکیده
Enzyme-Responsive Drug Release In article number 2102080, Zhengbao Zha, Hua Wang, and co-workers encapsulate chemotherapeutic DOX aTIGIT drugs together in a gelatin-based hydrogel to synergistically realize immunogenic tumors, which promote the infiltration of NK effector T cells then are further stimulated by subsequently released aTIGIT, boost multilayered innate adaptive immune responses for durable long-lasting anti-tumor therapy.
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ژورنال
عنوان ژورنال: Advanced Healthcare Materials
سال: 2022
ISSN: ['2192-2640', '2192-2659']
DOI: https://doi.org/10.1002/adhm.202270006